About me

I’ve spent my career studying how ideas evolve, first in the lab and then in venture. With a PhD in Chemistry and an MS in Pharmacology, I began by chasing molecules, mechanisms, and data. Over time, I recognized a gap between science and the business of science and decided to work in that space. My focus shifted toward what happens next: how belief turns experiments into enterprises, and how conviction turns science into strategy.

As an investor, I focus on bioscience and deep-tech ventures that translate discovery into lasting value. My work has taken me from Flagship Pioneering to BASF, Celgene, and now Connecticut Innovations, where I continue to look for ideas that outlive the hype cycle.

Books have always been the throughline—arguably a cheaper habit than starting companies. What began as casual book discussions with friends became a recurring way of learning: using other people’s work as case studies before repeating the same mistakes ourselves. Many of the ideas that move industries start as words on a page—frameworks, theories, and narratives—long before they become balance sheets or breakthroughs.

I created Build / Bet / Break to explore that process, one book, one idea, one conversation at a time. It’s now part book club, part podcast, and part ongoing inquiry into how conviction scales. At its core, it’s a way to preserve curiosity and rigor in how we build, fund, and understand progress.

When I’m not reading, I’m an aspiring Ashtangi, a weekend baker (on-brand for a chemist), and a traveler with a long-standing affection for U.S. national parks (49 / 63) and faraway places (53 countries). I accept gifts in plant form—Drosera capensis preferred. My cat, Jerry, is my constant companion and most consistent editor, though he remains skeptical of deadlines.

Dr. Jerry Madhav Unhelkar; PhD in "Cat"alysis